Senior narcotics agents Hazuki and Tsukasa have hated the drug trade since childhood under the influence of their former bureau-executive father. Hazuki is captured while investigating a gang distributing illegal drugs, and Tsukasa walks into a trap while attempting a solo rescue, leaving both adult sisters imprisoned. Their captors inject them with a powerful aphrodisiac drug that draws out their hidden masochistic desires. They fight back with trained minds and bodies, but their fate remains uncertain as the drug-fueled torture intensifies.