Doctor Cruel is a brilliant researcher with unmatched knowledge of drugs, a deep resentment toward women, and an obsessive desire to conquer them. At his deranged torture laboratory, he finally completes a supercharged aphrodisiac and joins forces with the evil Black Lion Society. After encountering the defiant Shizune in town, he restrains her and takes her away as a test subject. Unable to move, she is forced to swallow the drug; her body reacts despite her resistance, and the society’s men continue to torment and fondle her. Overwhelming pleasure drives her through violent spasms and forced orgasms until her sense of self collapses, leaving her fate uncertain after she passes her limit.